As far as her friends and teachers are concerned,Ashdod is an ordinary, bright, playful 5-year-old girl. They might be surprised to learn that not long ago therapists(治疗专家) were fighting to keep her from suffering from autism (孤独症)--a brain disorder that afflicts one in 100 children, typically leaving them with lifelong difficulties in communicating, socializing and carrying out many basic tasks.Ashdod was lucky: when she was 10 months old, her parents became alarmed that she had little interest in looking them in the eyes, eating and moving from her back, and took her to the MifneCenter in Rosh Pinna, Israel, a clinic that focuses on children 5 months and older who show early warning signs of autism. The results of the Mifne treatment were shocking, recalls the girl’s mother, TikvA、"Now she goes to a regular school where she is the same sort of active, funny, normal child as anyone else," she says. Despite a big jump in autism awareness in the past decade, parents, schools and doctors still frequently ignore warning signs in very young children. These can be difficult to detect: a child never points at things, shows more interest in objects than people, has delayed speech and develops a fascination with toys turning arounD、Many experts regard these symptoms as harmless habits that kids will outgrow. New research and experience in some autism clinics, however, suggests that starting treatment by age 2 is critical to mitigating and in some cases entirely avoiding the disorder. That’s because unlike the brain of an adult or even an older child, a 12-or 18-month-old’s brain is, in a sense, highly reprogrammable--that is, it responds well to treatments designed to permanently change basic patterns of thought and behavior. "All the evidence we have suggests that outcomes for these children will be better with an earlier diagnosis(诊断), before they reach 18 months, if possible," saysChristopher Gillberg, a professor at Gothenburg University in Sweden. Although there are currently no effective treatments for autism symptoms in older children or adults, the prospects are turning out to be entirely different for very young children who get prompt treatment. Psychologists have had remarkable success with behavioral therapy, which involves therapists working intensively with children to get them to do tasks they’re having difficulty with. The MifneCenter in Israel applies its own form of intensive therapy, typically lasting about two weeks and focusing on getting the child to make contact with parents and to eat and move normally. Some 200 children have been through the program; about three quarters have remained free of any signs of autism or any other significant developmental disorder, according to Mifne founder and director HannaAlonim. "If we can get them here as babies, close to 100 percent won’t develop autism." she says. "If we don’t see them until they’re 2. it’s a different story." To support Mifne’s findings with more-formal research, doctors at the TelAviv Sourasky MedicalCenter have begun screening and videotaping infants thought to be at risk of pre-autism before the Mifne treatment. Having a treatment choice for infants raises the hard issue of diagnosis.Autism can be tricky to recognize--it encompasses any or all of a broad range of symptoms, including difficulty with social interactions, language, motor skills and taking in sensory information, as well as repetitive behaviors. eating problems and in some cases unusually high or low levels of activity.A、study of nearly 10, 000 children inBergen. Norway, indicated that the number of children who showed "pronounced autistic features" was about five times higher than the number who qualified for a formal diagnosis of autism. Even children who exhibit only partial or mild versions of autism symptoms are at risk of ending up with lifelong challenges, say researchers, and would benefit from autism