Globally, alcohol consumption has increased in recent decades, with all or most of that increase in developing countries. This increase is often occurring in countries with few methods of prevention, control or treatment. The rise in alcohol consumption in developing countries provides ample cause for concern over the possible rise in alcohol related problems in those regions of the worlD、There is increasing evidence that besides volume of alcohol, the pattern of the drinking is relevant for the health outcomes. Overall, there is a causal relationship between alcohol consumption and more than 60 types of disease and injury. Worldwide alcohol costs 2.5 million death, 3.8% of total. The burden is not equally distributed among all the countries.